AI maps 766 genes linked to schizophrenia

A Nature Genetics study identified 766 genes associated with schizophrenia, including 641 absent from earlier transcriptomic analyses, by combining gene-expression networks with genetic data across six post-mortem brain regions and 62 Psychiatric Genomic Consortium cohorts. The paper reports that its trans-regulatory model predicted up to 1.8× as many genes as a cis-only baseline in an independent GTEx test, while Wired’s report places the work in the context of data from more than 102,000 people. The result is a map of biological coordination, not a diagnostic tool: life-science teams should treat it as a hypothesis-generation layer and wait for experimental validation before turning network associations into targets, following the archive’s evidence gate for AI-assisted wet-lab work.